Description

What is Semaglutide (20 mg)?

Semaglutide (20 mg) is a synthetic peptide commonly studied in metabolic and endocrine research. It is a modified analog of glucagon-like peptide-1 (GLP-1), involved in glucose signaling and metabolic regulation.

This peptide has specific structural modifications, including an amino acid change and the addition of a fatty acid side chain. These modifications enhance its stability and prolong its interaction with receptors in experimental systems, distinguishing it from native GLP-1, which is rapidly degraded in the body.

Semaglutide (20 mg) is ideal for extended research workflows, repeated assays, and large experimental series that require a steady supply of peptide material. This product is strictly for laboratory research use.

Product Specifications

CAS Number: 910463-68-2
Synonym: NN9535
Peptide Sequence: H-His-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gly-Gln-Ala-Ala-Lys(AEEAc-AEEAc-γ-Glu-17-carboxyheptadecanoyl)-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-OH
Molecular Formula: C₁₈₇H₂₉₁N₄₅O₅₉
Molecular Weight:6 g/mol
Purity: ≥95% (verified by HPLC and mass spectrometry)
Packaging Format: 20 mg lyophilized powder in sealed research-grade vial
Storage Conditions: Store 2–8 °C (≤–20 °C long term). Protect from light.
Intended Use: For Laboratory Research Use Only

Key Characteristics of Semaglutide (20 mg)

Synthetic GLP-1 receptor agonist analog designed for controlled research
Structural modifications improve resistance to rapid enzymatic breakdown in experimental models
Fatty acid side-chain enhances receptor interaction duration in vitro
High purity verified through HPLC and mass spectrometry
Supplied as a lyophilized powder to maintain integrity before reconstitution
Suitable for metabolic, endocrine, and receptor-signaling research
Compatible with standard peptide preparation, dilution, and assay methods

How Semaglutide (20 mg) Supports Research

Semaglutide (20 mg) is widely used to study GLP-1 receptor-mediated signaling and related metabolic pathways. Researchers use this peptide to explore receptor activation, second-messenger cascades (e.g., cAMP production), and downstream effects on cellular metabolism in controlled laboratory and preclinical environments.

With its enhanced stability compared to native GLP-1, Semaglutide facilitates the investigation of prolonged receptor engagement and time-dependent signaling responses. It is particularly useful for studying receptor desensitization, sustained signaling pathway activation, and for comparative studies with other GLP-1 receptor agonists.

Research Applications & Usage Information

Semaglutide (20 mg) is typically used in laboratory research focused on:

GLP-1 receptor binding and activation assays
Incretin hormone signaling pathway studies
Glucose metabolism and endocrine regulation
Cellular signaling and second-messenger pathway analysis
Comparative studies of short-acting vs. long-acting GLP-1 analogs
Preclinical metabolic model research

All applications are investigational and limited to controlled laboratory settings.

Handling and Storage Recommendations

Store at 2–8 °C (≤–20 °C for long-term storage). Protect from light.
Keep vials tightly sealed when not in use.
Minimize exposure to moisture and direct light during handling.
Allow vials to equilibrate before opening to prevent condensation.
After reconstitution, store solutions at 2–8 °C according to laboratory protocols.
Avoid repeated freeze-thaw cycles to support research applications.

Research Use Only Notice

This product is intended for laboratory research use only and is not approved for human or veterinary use. It is not intended for diagnostic, therapeutic, or clinical applications. Any reference to biological activity or potential effects is based solely on preclinical or in-vitro findings and should not be interpreted as validated clinical outcomes. Researchers are responsible for ensuring proper handling, storage, and disposal in accordance with institutional, federal, and international guidelines.